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Acute Myeloid Leukaemia India | Treatment Signs Causes & Cost (AML)


What is Acute myeloid leukemia (AML)?

Acute Myeloid Leukaemia India

Acute myeloid leukaemia (AML) is a type of cancer that affects the blood and bone marrow. AML is not a single disease. It is the name given to a group of leukaemias that develop in the myeloid cell line in the bone marrow. Myeloid cells are red blood cells, platelets and all white blood cells excluding lymphocytes.

AML is characterised by an overproduction of immature white blood cells, called myeloblasts or leukaemic blasts. These cells crowd the bone marrow, preventing it from making normal blood cells. They can also spill out into the bloodstream and circulate around the body. Due to their immaturity, they are unable to function properly to prevent or fight infection. Inadequate numbers of red cells and platelets being made by the marrow can cause anaemia, easy bleeding, and/or bruising.

You may hear other names for acute myeloid leukemia. Doctors may call it:
  • Acute myelocytic leukemia
  • Acute myelogenous leukemia
  • Acute granulocytic leukemia
  • Acute non-lymphocytic leukemia

 Signs and Symptoms of Acute Myeloid Leukemia (AML)

Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML.

General symptoms

People with AML often have several non-specific (general) symptoms. These can include:

Weight loss
Fatigue
Fever
Night sweats
Loss of appetite

These are not just symptoms of AML. More often they are caused by something other than leukemia.

Symptoms caused by low numbers of blood cells

Many signs and symptoms of AML are the results of a shortage of normal blood cells, which happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. These shortages show up on blood tests, and they can also cause symptoms.

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